Category A: Category A consists of one or more clinical conditions listed below in an adult or adolescent of above 13 years of age with confirmed HIV infection in laboratory investigation. But the patient should not have any condition which is listed in Category B or C.
1) Persistent generalized lymphadenopathy.
2) Asymptomatic HIV infection.
3) Primary HIV infection with accompanying illness or history of acute HIV infection.
Category B: Consists of symptomatic conditions in an HIV-infected adults or adolescent of more than 13 years of age. Condition should not be included among conditions listed in clinical category C. Should meet at least one of the following criteria a) The conditions are attributed to HIV infection or are indicative of a defect in cell-mediated immunity (reduced CD4+T cell count). b) The conditions are considered by physicians to have a clinical course or to require management that is complicated by HIV infection. The following are some of the examples:
1) Constitutional symptoms, such as fever (38.5°C) or diarrhea lasting more than 1 month.
2) Cervical dysplasia (moderate or severe) or cervical carcinoma in situ.
3) Bacillary angiomatosis.
4) Oropharyngeal candidiasis (thrush).
5) Vulvovaginal candidiasis, persistent, frequent, or poorly responsive to therapy.
6) Oral hairy leukoplakia.
7) Idiopathic thrombocytopenic purpura.
8 ) Herpes zoster (shingles), involving at least two distinct episodes or more than one dermatome.
9) Pelvic inflammatory disease, particularly if complicated by tubo ovarian abscess.
10) Peripheral neuropathy.
Category C: Conditions listed in AIDS surveillance case definition.
1) Candidiasis of bronchi, trachea, or lungs.
2) Esophageal candidiasis.
3) Invasive cervical cancer.
4) Extrapulmonary cryptococcosis.
5) Disseminated or extrapulmonary coccidioidomycosis.
6) Chronic intestinal cryptosporidiosis (more than 1 month’s duration).
7) Cytomegalovirus disease (other than liver, spleen, or nodes).
8 ) Cytomegalovirus retinitis (with loss of vision).
9) HIV-related encephalopathy.
10) Herpes simplex: chronic ulcer (more than 1 month’s duration); or bronchitis, pneumonia, or esophagitis.
11) Disseminated or extrapulmonary histoplasmosis.
12) Chronic intestinal isosporiasis, (more than 1 month’s duration).
13) Kaposi’s sarcoma.
14) Burkit’s Lymphoma (or equivalent term).
15) Primary lymphoma of brain.
16) Mycobacterium avium complex or M. kansasii, disseminated or extrapulmonary.
17) Mycobacterium tuberculosis, any site (pulmonary or extrapulmonary).
18 ) Mycobacterium, other species or unidentified species, disseminated or extrapulmonary.
19) Pneumocystis jiroveci pneumonia (formerly P. carinii).
20) Recurrent pneumonia.
21) Progressive multifocal leukoencephalopathy.
22) Recurrent Salmonella septicemia.
23) Toxoplasmosis of brain.
24) Wasting syndrome due to HIV.
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